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Hypertonia on the unaffected side will be addressed through rehabilitation. Botulinum toxin corrugator , frontalis, and depressor anguli oris muscles, as well as into the crow's feet and the quadratus mentalis muscle.
Even though the face loses some of its expressiveness, patients are generally very satisfied. The blockade of acetylcholine exocytosis by the toxin at the motor endplate is permanent, but the effect is reversible through axonal regrowth. The effect is maximal after 2 to 4 weeks. Sessions are recommended spaced 3 to 6 months apart. After 5 to 10 sessions, the effect can become permanent.
